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Noteworthy News and Research

Resveratrol

New Pill Has Promising List Of Benefits

Some doctors are saying if the early indications are true, a new pill could change health care.

They're talking about Resveratrol and some local doctors and patients are at the forefront of the research.

What if you were told that one little pill could help boost your energy, prevent cancer, control your weight, treat diabetes, improve your memory, your heart health and your skin?

That's the early indication for this supplement called Resveratrol.

Mount Lebanon friends Wendy Pollice and Christine Tumpson started taking it a few months ago.

"Right away I noticed that I didn't need as much sleep. Before eight hours a night, now getting by on six and a half and feeling great. Before It felt like I needed a nap. That doesn't happen anymore," Pollice said.

"After a couple months, I noticed that my skin looked better and that's my big excitement. My age spots were fading and it's just, my skin felt and looked better," Tumpson said.

Resveratrol is found naturally in red wine and now, highly respected doctors are recommending it to patients.

UPMC doctors Bryan Donahue, and Joseph Maroon are big proponents of Resveratrol. So much so, that Dr. Donahue invested in one of the supplements.

If you look at the basic science of this, it would take your breath away," Dr. Donahue said.

Resveratrol is also found naturally in peanuts, blueberries and some other foods, but it's concentrated in the pill, equivalent to 1,000 bottles of red wine.

Dr. Maroon's book about Resveratrol, called "The Longevity Factor," explains that the only thing scientists know will increase longevity is an extremely low-calorie diet.

The list of benefits from Resveratrol is long, based mostly on animal studies and some small human trials.

It includes:

  • Cancer prevention
  • Diabetes control
  • Weight control
  • Increased strength and endurance
  • Memory enhancement
  • Improved cardiovascular health

Former Steeler Rocky Bleier, a patient of doctors Donahue and Maroon, also takes Resveratrol.

"I've noticed a difference. I have more energy. I don't get that afternoon lull," Bleier said.

However, it's of all the benefits you can't see and feel that really has patients and doctors excited about Resveratrol.

Doctors Donahue and Maroon said if you're on blood thinners, you should definitely talk to your doctor before taking Resveratrol.

They said the people who will actually notice the biggest impact will be people who are already overweight or sedentary.

Critics point to the fact that most of the studies have been on animals and just now, the human studies are starting.

(© MMX, CBS Broadcasting Inc. All Rights Reserved.)

Featured Slideshows On KDKA.com


WHY IODINE??

RDA for Iodine                                                  

Pregnancy=220mcg/day

Adult Males and Females= 150mcg/day               

Lactation=290mcg/day

These levels were set up to prevent goiter only without concern for other body tissue requirements.

 

National Health & Nutrition Survey (NHANES) showed that iodine levels in the United States declined 50% while thyroid illness, breast, prostate, endometrial and ovarian cancers increased.

The World Health Organization (WHO) claims that an iodine deficiency is the world’s greatest single cause of preventable mental retardation.

 72% of the world’s population is affected by iodine deficiency.

Why Are We Deficient in Iodine?

v      Fear of using salt on medical advice, especially those with hypertension.

v      Less than 50% of households in United States use iodized salt.

v      Radioactive iodine used in diagnostic testing exacerbated an iodine-deficient state.

v      Exposures to chemicals and toxins. Goitrogen is a substance that decreases iodine uptake as well as inhibits iodine from binding where it is needed.

They include: Chlorine in pools, cleaning products, water supply, steam from dishwasher, sucrolose (Splenda).

v      Fluoride in water supply, toothpaste, dental treatments, mouthwash.

v      Bromide in some soft drinks (Mountain Dew & some Gatorades), baked goods (they used to contain iodine but it was replaced with bromide in the 1970’s), pesticides, hot tubs, fumigant of produce, and some medications

v      Declining mineral levels due to soil erosion and poor farming techniques.

v      Failure to eat sufficient iodine-containing foods.

v      A combination of any or all of these.

Iodine:

  • ­ Is essential for normal growth and development of children
  • Deficiency can result in cretinism, mental deficiency, delayed physical and intellectual development and ADHD
  • Elevates pH
  • Is needed to produce thyroid hormones
  • Prevents goiter, autoimmune thyroid conditions, thyroid and other cancers, hypothyroidism
  • Is antibacterial, antiviral and antiparasitic
  • Is a mucolytic agent (breaks up mucous)

 

Conditions Treated with Iodine

ADD                                          Parotid Duct Stones                     Headaches and Migraine

Breast Disease                             Peyronie’s                                  Keloids

Dupuytren’s Contracture              Sebaceous Cysts                         Headaches

Excess Mucous ProductioN           Thyroid Disorders                         Ovarian Cysts

Fatigue                                      Cancer (breast, ovarian, thyroid, prostate) Fibrocystic Breasts

Hemorrhoids

Taken from Iodine, Why You Need It, Why You Can’t Live Without It, by David Brownstein, M..D. Medical Alternative Press, 2004 along with lecture notes.  Visit www.drbrownstein.com.

                                                                                  

Medical Iodophobia

“Medical Iodophobia is the unwarranted fear of using and recommending inorganic, non-radioactive iodine/iodide within the range known from collective experience of three generations of clinicians to be the safest and most effective amounts for treating symptoms and signs of iodine/iodide deficiency. (12.5-50 mg. /day)” Dr. Guy Abraham, 2004

 

IODINE FACTS:

  1. The studies from Mexico and India suggest that iodine can inhibit proliferation of thyroid and human breast cancer cells.
  2.  “The breasts are one of the body’s main storage sites for iodine in the body. In an iodine-deficient state, the thyroid gland and the breasts will compete for what little iodine is available.”
  3.  “Iodine has been shown to induce apoptosis (death) in breast and thyroid cancer cells”
  4. “It is known that ovaries concentrate a large amount of iodine. After the thyroid, the ovaries have the second largest concentration of iodine in the body.  Iodine deficiency produces changes in the ovarian production of estrogens as well as changes in the estrogen receptors of the breasts.  In an iodine deficient state, research has shown that ovarian estrogen production increases, while estrogen receptors in the breast increase their sensitivity to estrogens.  Both of these conditions will increase the risk of developing pathology of the breasts, including breast cancer.” 
  5. “Fibrocystic breast disease is a very common condition which is found in up to 2/3 of women, that responds very well to iodine therapy.”
  6. “Research in animals has shown that the correction of iodine deficiency results in abnormal breast tissue changing back to normal breast tissue.”

 Iodine-Why You Need It, Why You Can’t Live Without It. By David Brownstein, M.D. Pgs 71,77,78,25

 Note: Animal research shows that excessive iodine intake suppresses selenium levels and selenium dependent enzymes including glutathione peroxidase and the deiodinase 1 enzyme essential to thyroid health. The high iodine intake, in the presence of selenium deficiency, results in a decrease in total T3. At least three deiodinase isoenzymes have so far been characterized and are called selenoproteins. Selenium status apparently regulates the expression of these deiodinase isozymes to a different extent indicating that a hierarchy of selenium incorporation exists for these enzymes.

 Take home: When supplementing patients with mg doses of iodine, it may be prudent to make sure their supplement regimen includes 200 mcg selenium as well.

 Source: Effect of selenium supplementation on activity and mRNA expression of type 1 deiodinase in mice with excessive iodine intake.

Taken from Iodine, Why You Need It, Why You Can’t Live Without It, by David Brownstein, M.D. Medical Alternative Press, 2004 along with lecture notes.  These Statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure, or prevent any disease.



First Magazine Article featuring Dr. Randolph & Genie James

First Magazine has recently accessed C.W. Randolph Jr., M.D. and Genie James, M.M. Sc., co-founders of the Natural Hormone Institute, as medical experts on key women's health topics including groundbreaking news on options for hormone replacement therapy.  First is available on newsstands across the country.  In the meantime, be sure to check out the latest news on bioidentical hormone replacement therapy and hormone health.  See link below.


Medco Thyroid Scandal: Thyroid Patients Demand Answers Regarding Misleading Thyroid Drug Shortage No

By Mary Shomon, About.com

About.com Health's Disease and Condition content is reviewed by our Medical Review Board


Healthy hormone levels lower cholesterol


A study published in the October-December 2004 issue of the Ukrainian journal The Health of Donbass, demonstrated that restoring hormones to youthful levels in patients with elevated lipids dramatically lowered cholesterol and triglycerides without resorting to the use of statin drugs.

Twenty-seven men and 46 women between the ages of 25 and 81 with elevated cholesterol levels were included in the current study. A lipid profile was obtained and the hormones pregnenolone, DHEA, progesterone, total estrogen and total testosterone were measured upon the participants’ initial visits and at several points during treatment. Subjects were treated with bioidentical pregnenolone and DHEA as oral supplements, and topical triestrogen, progesterone and testosterone gels. Hormone dosage was determined by hormone levels ascertained during the trial.

All of the participants were found to have lower total cholesterol levels after youthful hormone levels were restored, with total cholesterol dropping below 200 milligrams per deciliter in 61.6 percent of the group. Mean serum total cholesterol was reduced from 252 milligrams per deciliter before treatment to 192.8 milligrams per deciliter. Mean serum triglycerides were lowered by 35.5 percent. Men experienced a greater reduction in both cholesterol and triglycerides than women.

The authors propose that most cases of elevated cholesterol arise as a reaction to the age-related decline in hormone production. Because cholesterol is necessary for the production of hormones, the liver may overproduce cholesterol in an attempt to restore them by elevating their precursor. Lead researcher Sergey A Dr Dzugan, MD told Life Extension, “The findings support the hypothesis that hypercholesterolemia is a compensatory mechanism for life-cycle related down-regulation of steroid hormones and that broadband steroid hormone restoration is associated with a substantial drop in serum TC in many patients. This idea may be a very important in treating migraine, fibromyalgia, fatigue syndrome, depression, bipolar disorder and ADHD patients who often have many hormonal axes imbalanced. It is vital that the hormone levels be tests and the normal amounts restored using bio-identical to human hormones."

Information taken from www.lef.org


Insomnia

Insomnia

According to the National Sleep Foundation's 2002 Sleep in America poll, 58% of adults in this country reported at least one symptom of insomnia in the past year.

Sleep helps to organize memories, solidify learning, and improve concentration. Proper sleep, especially sleep where you are actively dreaming (REM sleep), regulates mood as well. Lack of sleep can make you irritable and cranky, affecting your emotions, social interaction, and decision making.

Sleep is essential to the health of the immune system. Without adequate sleep, the immune system becomes weak, and the body becomes more vulnerable to infection and disease. Sleep is also a time of rest and repair for neurons. Many hormones are timed to release during sleep or right before sleep. Growth hormone, for example, is released during sleep, vital to growing children but also for restorative processes like muscle repair.

Evidence suggests that people with insomnia have a ten-fold risk of developing depression and anxiety compared with those who sleep well. Half of those who have experienced insomnia blame the problem on stress and worry.

From peri-menopause to post-menopause, women report the most sleeping problems. The ovaries gradually decrease production of estrogen and progesterone, a sleep promoting hormone. Common sleep disrupters include hot flashes, mood disorders, and sleep-disordered breathing (associated with sleep apnea).

Accumulating evidence from both epidemiologic studies and well-controlled laboratory studies indicates that chronic partial sleep loss may increase the risk of obesity. Sleep restriction results in metabolic and endocrine alterations, including decreased glucose tolerance, decreased insulin sensitivity, increased evening concentrations of cortisol, and increased hunger and appetite. Altogether, the evidence points to a possible role of decreased sleep duration in the current epidemic of obesity. Sometimes the best way to treat obesity can be to treat an underlying sleep problem.

In order to sleep better at night and reduce daytime sleepiness, try practicing the following sleep tips:

° Maintain a regular bed and wake time schedule, including weekends
° Establish a regular, relaxing bedtime routine such as taking a bath or listening to music
° Create a sleep-conducive environment that is dark, quiet, comfortable and cool
° Sleep on a comfortable mattress and pillows
° Use your bedroom only for sleep and sex
° Finish eating at least 2-3 hours before your regular bedtime
° Exercise regularly but avoid it a few hours before bedtime
° Avoid caffeine (e.g. coffee, tea, soft drinks, chocolate) close to bedtime
° Don't smoke -- not only is it a major health risk it can lead to poor sleep
° Avoid alcohol close to bedtime; it can lead to disrupted sleep later in the night
° If you can't go to sleep after 30 minutes, don't stay in bed tossing and turning. Get up and involve yourself in a relaxing activity, such as listening to soothing music or reading, until you feel sleepy. Remember: Try to clear your mind; don't use this time to solve your daily problems.

When changing routine and environment is not enough to improve sleep, consider testing salivary hormone levels. Low estrogen, estrogen dominance, and unhealthy adrenal function can contribute to insomnia.

Low estrogen levels may contribute to hot flashes and night sweats that interrupt sleep. High nighttime cortisol levels are associated with low melatonin levels, and difficulty sleeping is a very common symptom associated with low cortisol levels and adrenal fatigue. And finally, when progesterone levels are low or suboptimal and insomnia is present, transdermal progesterone can promote drowsiness. And for providers with prescription privileges, oral progesterone is a wonderful supplement as it is metabolized to allopregnenolone and stimulates GABA receptors to encourage sleep.

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4227 Murray Avenue
Pittsburgh, PA 15217  USA

Store Phone: 412-421-4996
Store FAX: 412-421-6500
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